Evaluation of Cx43 Gap Junction Inhibitors Using a Quantitative Structure-Activity Relationship Model

Gap junctions (GJs) made of connexin-43 (Cx43) are necessary for the conduction of electrical impulses in the heart. Modulation of Cx43 GJ activity may be beneficial in the treatment of cardiac arrhythmias and other dysfunctions. The search for novel GJ-modulating agents using molecular docking allo...

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Detalles Bibliográficos
Autores principales: Matusevičiūtė, Ramona, Ignatavičiūtė, Eglė, Mickus, Rokas, Bordel, Sergio, Skeberdis, Vytenis Arvydas, Raškevičius, Vytautas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377234/
https://www.ncbi.nlm.nih.gov/pubmed/37509611
http://dx.doi.org/10.3390/biomedicines11071972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377234/
https://www.ncbi.nlm.nih.gov/pubmed/37509611
http://dx.doi.org/10.3390/biomedicines11071972

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