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Biocompatible Phosphorescent O(2) Sensors Based on Ir(III) Complexes for In Vivo Hypoxia Imaging

In this work, we obtained three new phosphorescent iridium complexes (Ir1–Ir3) of general stoichiometry [Ir(N^C)(2)(N^N)]Cl decorated with oligo(ethylene glycol) fragments to make them water-soluble and biocompatible, as well as to protect them from aggregation with biomolecules such as albumin. The...

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Detalles Bibliográficos
Autores principales: Samandarsangari, Mozhgan, Kozina, Daria O., Sokolov, Victor V., Komarova, Anastasia D., Shirmanova, Marina V., Kritchenkov, Ilya S., Tunik, Sergey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377268/
https://www.ncbi.nlm.nih.gov/pubmed/37504079
http://dx.doi.org/10.3390/bios13070680