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Technological Convergence: Highlighting the Power of CRISPR Single-Cell Perturbation Toolkit for Functional Interrogation of Enhancers

SIMPLE SUMMARY: Enhancers serve as logic gates of the regulatory mechanism of gene expression, and their malfunction is associated with numerous diseases. Therefore, the functional validation of enhancer elements is of great importance in genomics research. Recent technological advancements have ena...

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Detalles Bibliográficos
Autores principales: Ghamsari, Reza, Rosenbluh, Joseph, Menon, A Vipin, Lovell, Nigel H., Alinejad-Rokny, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377346/
https://www.ncbi.nlm.nih.gov/pubmed/37509229
http://dx.doi.org/10.3390/cancers15143566