The Prognostic and Predictive Value of Human Gastrointestinal Microbiome and Exosomal mRNA Expression of PD-L1 and IFNγ for Immune Checkpoint Inhibitors Response in Metastatic Melanoma Patients: PROTOCOL TRIAL

Background: Immunotherapy has been successful in treating advanced melanoma, but a large proportion of patients do not respond to the treatment with immune checkpoint inhibitors (ICIs). Preclinical and small cohort studies suggest gastrointestinal microbiome composition and exosomal mRNA expression...

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Detalles Bibliográficos
Autores principales: Erman, Ana, Ignjatović, Marija, Leskovšek, Katja, Miceska, Simona, Lampreht Tratar, Urša, Bošnjak, Maša, Kloboves Prevodnik, Veronika, Čemažar, Maja, Kandolf Sekulovič, Lidija, Avguštin, Gorazd, Ocvirk, Janja, Mesti, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377397/
https://www.ncbi.nlm.nih.gov/pubmed/37509655
http://dx.doi.org/10.3390/biomedicines11072016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377397/
https://www.ncbi.nlm.nih.gov/pubmed/37509655
http://dx.doi.org/10.3390/biomedicines11072016

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