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The Prognostic and Predictive Value of Human Gastrointestinal Microbiome and Exosomal mRNA Expression of PD-L1 and IFNγ for Immune Checkpoint Inhibitors Response in Metastatic Melanoma Patients: PROTOCOL TRIAL
Background: Immunotherapy has been successful in treating advanced melanoma, but a large proportion of patients do not respond to the treatment with immune checkpoint inhibitors (ICIs). Preclinical and small cohort studies suggest gastrointestinal microbiome composition and exosomal mRNA expression...
Autores principales: | Erman, Ana, Ignjatović, Marija, Leskovšek, Katja, Miceska, Simona, Lampreht Tratar, Urša, Bošnjak, Maša, Kloboves Prevodnik, Veronika, Čemažar, Maja, Kandolf Sekulovič, Lidija, Avguštin, Gorazd, Ocvirk, Janja, Mesti, Tanja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377397/ https://www.ncbi.nlm.nih.gov/pubmed/37509655 http://dx.doi.org/10.3390/biomedicines11072016 |
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