Interleukin-19 Gene-Deficient Mice Promote Liver Fibrosis via Enhanced TGF-β Signaling, and the Interleukin-19-CCL2 Axis Is Important in the Direction of Liver Fibrosis

IL-19 is a cytokine discovered by homologous searching with IL-10 and is produced by non-immune cells, such as keratinocytes, in addition to immune cells, such as macrophages. Liver fibrosis results from the inflammation and activation of hepatic stellate cells via chronic liver injury. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Ono, Naoshige, Fujita, Takashi, Miki, Mariko, Nishiyama, Kazuhiro, Izawa, Takeshi, Aoyama, Tomoko, Kuwamura, Mitsuru, Fujii, Hideki, Azuma, Yasu-Taka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377488/
https://www.ncbi.nlm.nih.gov/pubmed/37509702
http://dx.doi.org/10.3390/biomedicines11072064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377488/
https://www.ncbi.nlm.nih.gov/pubmed/37509702
http://dx.doi.org/10.3390/biomedicines11072064

Ejemplares similares