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Interleukin-19 Gene-Deficient Mice Promote Liver Fibrosis via Enhanced TGF-β Signaling, and the Interleukin-19-CCL2 Axis Is Important in the Direction of Liver Fibrosis
IL-19 is a cytokine discovered by homologous searching with IL-10 and is produced by non-immune cells, such as keratinocytes, in addition to immune cells, such as macrophages. Liver fibrosis results from the inflammation and activation of hepatic stellate cells via chronic liver injury. However, the...
Autores principales: | Ono, Naoshige, Fujita, Takashi, Miki, Mariko, Nishiyama, Kazuhiro, Izawa, Takeshi, Aoyama, Tomoko, Kuwamura, Mitsuru, Fujii, Hideki, Azuma, Yasu-Taka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377488/ https://www.ncbi.nlm.nih.gov/pubmed/37509702 http://dx.doi.org/10.3390/biomedicines11072064 |
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