Application of I-Optimal Design for Modeling and Optimizing the Operational Parameters of Ibuprofen Granules in Continuous Twin-Screw Wet Granulation

The continuous twin-screw wet granulation (TSWG) process was investigated and optimized with prediction-oriented I-optimal designs. The I-optimal designs can not only obtain a precise estimation of the parameters that describe the effect of five input process parameters, including the screw speed, l...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Tian, Geng, Qu, Haibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377492/
https://www.ncbi.nlm.nih.gov/pubmed/37509668
http://dx.doi.org/10.3390/biomedicines11072030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377492/
https://www.ncbi.nlm.nih.gov/pubmed/37509668
http://dx.doi.org/10.3390/biomedicines11072030

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