Cargando…

δ-Opioid Receptor as a Molecular Target for Increasing Cardiac Resistance to Reperfusion in Drug Development

An analysis of published data and the results of our own studies reveal that the activation of a peripheral δ(2)-opioid receptor (δ(2)-OR) increases the cardiac tolerance to reperfusion. It has been found that this δ(2)-OR is localized in cardiomyocytes. Endogenous opioids are not involved in the re...

Descripción completa

Detalles Bibliográficos
Autores principales: Naryzhnaya, Natalia V., Mukhomedzyanov, Alexander V., Sirotina, Maria, Maslov, Leonid N., Kurbatov, Boris K., Gorbunov, Alexander S., Kilin, Mikhail, Kan, Artur, Krylatov, Andrey V., Podoksenov, Yuri K., Logvinov, Sergey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377504/
https://www.ncbi.nlm.nih.gov/pubmed/37509526
http://dx.doi.org/10.3390/biomedicines11071887