Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases

Multitarget drugs based on a hybrid dopamine–xanthine core were designed as potential drug candidates for the treatment of neurodegenerative diseases. Monoamine oxidase B (MAO-B) inhibitors with significant ancillary A(2A) adenosine receptor (A(2A)AR) antagonistic properties were further developed t...

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Detalles Bibliográficos
Autores principales: Załuski, Michał, Karcz, Tadeusz, Drabczyńska, Anna, Vielmuth, Christin, Olejarz-Maciej, Agnieszka, Głuch-Lutwin, Monika, Mordyl, Barbara, Siwek, Agata, Satała, Grzegorz, Müller, Christa E., Kieć-Kononowicz, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377586/
https://www.ncbi.nlm.nih.gov/pubmed/37509114
http://dx.doi.org/10.3390/biom13071079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377586/
https://www.ncbi.nlm.nih.gov/pubmed/37509114
http://dx.doi.org/10.3390/biom13071079

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