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Airway Epithelium Senescence as a Driving Mechanism in COPD Pathogenesis

Cellular senescence is a state of permanent cell cycle arrest triggered by various intrinsic and extrinsic stressors. Cellular senescence results in impaired tissue repair and remodeling, loss of physiological integrity, organ dysfunction, and changes in the secretome. The systemic accumulation of s...

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Detalles Bibliográficos
Autores principales: Bateman, Georgia, Guo-Parke, Hong, Rodgers, Aoife M., Linden, Dermot, Bailey, Melanie, Weldon, Sinéad, Kidney, Joseph C., Taggart, Clifford C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377597/
https://www.ncbi.nlm.nih.gov/pubmed/37509711
http://dx.doi.org/10.3390/biomedicines11072072