Cargando…
Airway Epithelium Senescence as a Driving Mechanism in COPD Pathogenesis
Cellular senescence is a state of permanent cell cycle arrest triggered by various intrinsic and extrinsic stressors. Cellular senescence results in impaired tissue repair and remodeling, loss of physiological integrity, organ dysfunction, and changes in the secretome. The systemic accumulation of s...
Autores principales: | Bateman, Georgia, Guo-Parke, Hong, Rodgers, Aoife M., Linden, Dermot, Bailey, Melanie, Weldon, Sinéad, Kidney, Joseph C., Taggart, Clifford C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377597/ https://www.ncbi.nlm.nih.gov/pubmed/37509711 http://dx.doi.org/10.3390/biomedicines11072072 |
Ejemplares similares
-
Deciphering Respiratory-Virus-Associated Interferon Signaling in COPD Airway Epithelium
por: Guo-Parke, Hong, et al.
Publicado: (2022) -
Mechanisms of Virus-Induced Airway Immunity Dysfunction in the Pathogenesis of COPD Disease, Progression, and Exacerbation
por: Guo-Parke, Hong, et al.
Publicado: (2020) -
Altered Differentiation and Inflammation Profiles Contribute to Enhanced Innate Responses in Severe COPD Epithelium to Rhinovirus Infection
por: Guo-Parke, Hong, et al.
Publicado: (2022) -
Respiratory viral infection: a potential “missing link” in the pathogenesis of COPD
por: Linden, Dermot, et al.
Publicado: (2019) -
Airway Inflammation and Host Responses in the Era of CFTR Modulators
por: Keown, Karen, et al.
Publicado: (2020)