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The Multiple Faces of the MRN Complex: Roles in Medulloblastoma and Beyond

SIMPLE SUMMARY: Defects in MRE11A/RAD50/NBS1 (MRN) genes and overexpression of the MRN proteins are both linked to cancer, generating confusion about how the MRN complex impacts cancer initiation and progression. In this review, we examined the most relevant studies on the topic, taking advantage of...

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Detalles Bibliográficos
Autores principales: Petroni, Marialaura, La Monica, Veronica, Fabretti, Francesca, Augusto, Mariaconcetta, Battaglini, Damiana, Polonara, Francesca, Di Giulio, Stefano, Giannini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377613/
https://www.ncbi.nlm.nih.gov/pubmed/37509263
http://dx.doi.org/10.3390/cancers15143599