The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo

A significant proportion of meningiomas are clinically aggressive, but there is currently no effective chemotherapy for meningiomas. An increasing number of studies have been conducted to develop targeted therapies, yet none have focused on the p53 pathway as a potential target. In this study, we ai...

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Detalles Bibliográficos
Autores principales: Mitobe, Yuta, Suzuki, Shuhei, Nakagawa-Saito, Yurika, Togashi, Keita, Sugai, Asuka, Sonoda, Yukihiko, Kitanaka, Chifumi, Okada, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377688/
https://www.ncbi.nlm.nih.gov/pubmed/37509605
http://dx.doi.org/10.3390/biomedicines11071967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377688/
https://www.ncbi.nlm.nih.gov/pubmed/37509605
http://dx.doi.org/10.3390/biomedicines11071967

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