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Decoding Oncofusions: Unveiling Mechanisms, Clinical Impact, and Prospects for Personalized Cancer Therapies

SIMPLE SUMMARY: Oncofusions, or cancer-associated fusion mutations, are driving forces in cancer development. Advanced sequencing technologies have revolutionized their identification, opening new avenues in cancer research. Oncofusions manipulate cellular signaling pathways and show promise as targ...

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Detalles Bibliográficos
Autores principales: Salokas, Kari, Dashi, Giovanna, Varjosalo, Markku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377698/
https://www.ncbi.nlm.nih.gov/pubmed/37509339
http://dx.doi.org/10.3390/cancers15143678