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Nanobody-Based EGFR-Targeting Immunotoxins for Colorectal Cancer Treatment

Immunotoxins (ITXs) are chimeric molecules that combine the specificity of a targeting domain, usually derived from an antibody, and the cytotoxic potency of a toxin, leading to the selective death of tumor cells. However, several issues must be addressed and optimized in order to use ITXs as therap...

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Detalles Bibliográficos
Autores principales: Narbona, Javier, Hernández-Baraza, Luisa, Gordo, Rubén G., Sanz, Laura, Lacadena, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377705/
https://www.ncbi.nlm.nih.gov/pubmed/37509078
http://dx.doi.org/10.3390/biom13071042