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Nanobody-Based EGFR-Targeting Immunotoxins for Colorectal Cancer Treatment
Immunotoxins (ITXs) are chimeric molecules that combine the specificity of a targeting domain, usually derived from an antibody, and the cytotoxic potency of a toxin, leading to the selective death of tumor cells. However, several issues must be addressed and optimized in order to use ITXs as therap...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377705/ https://www.ncbi.nlm.nih.gov/pubmed/37509078 http://dx.doi.org/10.3390/biom13071042 |