Computational Analysis Reveals Unique Binding Patterns of Oxygenated and Deoxygenated Myoglobin to the Outer Mitochondrial Membrane

Myoglobin (Mb) interaction with the outer mitochondrial membrane (OMM) promotes oxygen (O(2)) release. However, comprehensive molecular details on specific contact regions of the OMM with oxygenated (oxy-) and deoxygenated (deoxy-)Mb are missing. We used molecular dynamics (MD) simulations to explor...

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Detalles Bibliográficos
Autores principales: Anishkin, Andriy, Adepu, Kiran Kumar, Bhandari, Dipendra, Adams, Sean H., Chintapalli, Sree V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377724/
https://www.ncbi.nlm.nih.gov/pubmed/37509174
http://dx.doi.org/10.3390/biom13071138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377724/
https://www.ncbi.nlm.nih.gov/pubmed/37509174
http://dx.doi.org/10.3390/biom13071138

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