CRISPR-Cas9 engineering in the hybrid yeast Zygosaccharomyces parabailii can lead to loss of heterozygosity in target chromosomes

The hybrid yeast Zygosaccharomyces parabailii holds potential as a cell factory mainly because of its robustness in withstanding stressors that often characterize bio-based processes. However, a complex genome and a lack of gene editing tools hinder the capacity to engineer this yeast. In this work,...

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Detalles Bibliográficos
Autores principales: Jayaprakash, Pooja, Barroso, Liliane, Vajente, Matteo, Maestroni, Letizia, Louis, Edward J, Morrissey, John P, Branduardi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377752/
https://www.ncbi.nlm.nih.gov/pubmed/37458780
http://dx.doi.org/10.1093/femsyr/foad036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377752/
https://www.ncbi.nlm.nih.gov/pubmed/37458780
http://dx.doi.org/10.1093/femsyr/foad036

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