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CRISPR-Cas9 engineering in the hybrid yeast Zygosaccharomyces parabailii can lead to loss of heterozygosity in target chromosomes
The hybrid yeast Zygosaccharomyces parabailii holds potential as a cell factory mainly because of its robustness in withstanding stressors that often characterize bio-based processes. However, a complex genome and a lack of gene editing tools hinder the capacity to engineer this yeast. In this work,...
Autores principales: | Jayaprakash, Pooja, Barroso, Liliane, Vajente, Matteo, Maestroni, Letizia, Louis, Edward J, Morrissey, John P, Branduardi, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377752/ https://www.ncbi.nlm.nih.gov/pubmed/37458780 http://dx.doi.org/10.1093/femsyr/foad036 |
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