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Identification of a Novel ERK5 (MAPK7) Inhibitor, MHJ-627, and Verification of Its Potent Anticancer Efficacy in Cervical Cancer HeLa Cells

Extracellular signal-regulated kinase 5 (ERK5), a member of the mitogen-activated protein kinase (MAPK) family, is involved in key cellular processes. However, overexpression and upregulation of ERK5 have been reported in various cancers, and ERK5 is associated with almost every biological character...

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Detalles Bibliográficos
Autores principales: Hwang, Jeonghye, Moon, Hyejin, Kim, Hakwon, Kim, Ki-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377775/
https://www.ncbi.nlm.nih.gov/pubmed/37504304
http://dx.doi.org/10.3390/cimb45070388