Evolving Acquired Vemurafenib Resistance in a BRAF V600E Mutant Melanoma PDTX Model to Reveal New Potential Targets

Malignant melanoma is challenging to treat, and metastatic cases need chemotherapy strategies. Targeted inhibition of commonly mutant BRAF V600E by inhibitors is efficient but eventually leads to resistance and progression in the vast majority of cases. Numerous studies investigated the mechanisms o...

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Detalles Bibliográficos
Autores principales: Tóvári, József, Vári-Mező, Diána, Surguta, Sára Eszter, Ladányi, Andrea, Kigyós, Attila, Cserepes, Mihály
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377807/
https://www.ncbi.nlm.nih.gov/pubmed/37508582
http://dx.doi.org/10.3390/cells12141919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377807/
https://www.ncbi.nlm.nih.gov/pubmed/37508582
http://dx.doi.org/10.3390/cells12141919

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