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Canadian Consensus Recommendations on the Management of KRAS G12C-Mutated NSCLC

Activating mutations in Kirsten rat sarcoma viral oncogene homologue (KRAS), in particular, a point mutation leading to a glycine-to-cysteine substitution at codon 12 (G12C), are among the most frequent genomic alterations in non-small cell lung cancer (NSCLC). Several agents targeting KRAS G12C hav...

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Detalles Bibliográficos
Autores principales: Cheema, Parneet K., Banerji, Shantanu O., Blais, Normand, Chu, Quincy S.-C., Juergens, Rosalyn A., Leighl, Natasha B., Sacher, Adrian, Sheffield, Brandon S., Snow, Stephanie, Vincent, Mark, Wheatley-Price, Paul F., Yip, Stephen, Melosky, Barbara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377814/
https://www.ncbi.nlm.nih.gov/pubmed/37504336
http://dx.doi.org/10.3390/curroncol30070476