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Adjunct Therapy with T Regulatory Cells Decreases Inflammation and Preserves the Anti-Tumor Activity of CAR T Cells

With greater accessibility and an increased number of patients being treated with CAR T cell therapy, real-world toxicity continues to remain a significant challenge to its widespread adoption. We have previously shown that allogeneic umbilical cord blood-derived (UCB) regulatory T cells (Tregs) can...

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Detalles Bibliográficos
Autores principales: Zeng, Ke, Huang, Meixian, Lyu, Mi-Ae, Khoury, Joseph D., Ahmed, Sairah, Patel, Krina K., Dropulić, Boro, Reese-Koc, Jane, Caimi, Paolo F., Sadeghi, Tara, de Lima, Marcos, Flowers, Christopher R., Parmar, Simrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377823/
https://www.ncbi.nlm.nih.gov/pubmed/37508543
http://dx.doi.org/10.3390/cells12141880