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Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Carcinogenesis by Modulating Microtubule-Associated Serine/Threonine Kinase-like/Wnt/β-Catenin Signaling

Background: Despite significant progress in clinical management, colorectal cancer (CRC) remains the third most common cause of cancer-related deaths. A positive association between PYCR2 (pyrroline-5-carboxylate reductase-2), a terminal enzyme of proline metabolism, and CRC aggressiveness was recen...

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Detalles Bibliográficos
Autores principales: Lama Tamang, Raju, Kumar, Balawant, Patel, Sagar M., Thapa, Ishwor, Ahmad, Alshomrani, Kumar, Vikas, Ahmad, Rizwan, Becker, Donald F., Bastola, Dundy (Kiran), Dhawan, Punita, Singh, Amar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377831/
https://www.ncbi.nlm.nih.gov/pubmed/37508547
http://dx.doi.org/10.3390/cells12141883