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NOXA Accentuates Apoptosis Induction by a Novel Histone Deacetylase Inhibitor

SIMPLE SUMMARY: Tumors in the pancreas and colon are still too often an unmet clinical problem. Cells from these cancers and normal cells have different gene expression profiles. Such dysregulation can be exploited with novel drugs that modulate the acetylation of proteins. We present KH16, a novel...

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Detalles Bibliográficos
Autores principales: Ashry, Ramy, Mustafa, Al-Hassan M., Hausmann, Kristin, Linnebacher, Michael, Strand, Susanne, Sippl, Wolfgang, Wirth, Matthias, Krämer, Oliver H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377841/
https://www.ncbi.nlm.nih.gov/pubmed/37509312
http://dx.doi.org/10.3390/cancers15143650