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Chronic Intermittent Hypoxia-Induced Diaphragm Muscle Weakness Is NADPH Oxidase-2 Dependent

Chronic intermittent hypoxia (CIH)-induced redox alterations underlie diaphragm muscle dysfunction. We sought to establish if NADPH oxidase 2 (NOX2)-derived reactive oxygen species (ROS) underpin CIH-induced changes in diaphragm muscle, which manifest as impaired muscle performance. Adult male mice...

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Detalles Bibliográficos
Autores principales: Drummond, Sarah E., Burns, David P., El Maghrani, Sarah, Ziegler, Oscar, Healy, Vincent, O’Halloran, Ken D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377874/
https://www.ncbi.nlm.nih.gov/pubmed/37508499
http://dx.doi.org/10.3390/cells12141834