Cargando…

Chronic Intermittent Hypoxia-Induced Diaphragm Muscle Weakness Is NADPH Oxidase-2 Dependent

Chronic intermittent hypoxia (CIH)-induced redox alterations underlie diaphragm muscle dysfunction. We sought to establish if NADPH oxidase 2 (NOX2)-derived reactive oxygen species (ROS) underpin CIH-induced changes in diaphragm muscle, which manifest as impaired muscle performance. Adult male mice...

Descripción completa

Detalles Bibliográficos
Autores principales:	Drummond, Sarah E., Burns, David P., El Maghrani, Sarah, Ziegler, Oscar, Healy, Vincent, O’Halloran, Ken D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377874/ https://www.ncbi.nlm.nih.gov/pubmed/37508499 http://dx.doi.org/10.3390/cells12141834

Ejemplares similares

NADPH oxidase 2 is necessary for chronic intermittent hypoxia‐induced sternohyoid muscle weakness in adult male mice
por: Drummond, Sarah E., et al.
Publicado: (2022)

Chronic intermittent hypoxia increases rat sternohyoid muscle NADPH oxidase expression with attendant modest oxidative stress
por: Williams, Robert, et al.
Publicado: (2015)

Effects of Gestational and Postnatal Exposure to Chronic Intermittent Hypoxia on Diaphragm Muscle Contractile Function in the Rat
por: McDonald, Fiona B., et al.
Publicado: (2016)

Diaphragm Muscle Weakness Following Acute Sustained Hypoxic Stress in the Mouse Is Prevented by Pretreatment with N-Acetyl Cysteine
por: O'Leary, Andrew J., et al.
Publicado: (2018)

Early Life Exposure to Chronic Intermittent Hypoxia Primes Increased Susceptibility to Hypoxia-Induced Weakness in Rat Sternohyoid Muscle during Adulthood
por: McDonald, Fiona B., et al.
Publicado: (2016)

Diaphragm Muscle Adaptation to Sustained Hypoxia: Lessons from Animal Models with Relevance to High Altitude and Chronic Respiratory Diseases
por: Lewis, Philip, et al.
Publicado: (2016)

HIF-1α Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase
por: Nanduri, Jayasri, et al.
Publicado: (2015)

The ups and downs of intermittent hypoxia as a therapy for ventilatory insufficiency
por: O'Halloran, Ken D.
Publicado: (2022)

N-acetylcysteine Decreases Fibrosis and Increases Force-Generating Capacity of mdx Diaphragm
por: Burns, David P., et al.
Publicado: (2019)

Tempol Supplementation Restores Diaphragm Force and Metabolic Enzyme Activities in mdx Mice
por: Burns, David P., et al.
Publicado: (2017)

NADPH oxidase mediates microtubule alterations and diaphragm dysfunction in dystrophic mice
por: Loehr, James Anthony, et al.
Publicado: (2018)

Correction: NADPH oxidase mediates microtubule alterations and diaphragm dysfunction in dystrophic mice
por: Loehr, James Anthony, et al.
Publicado: (2022)

Chronic intermittent asphyxia impairs rat upper airway muscle responses to acute hypoxia and asphyxia
por: O'Hare, T, et al.
Publicado: (2001)

Intermittent Hypoxia-Induced Cognitive Deficits Are Mediated by NADPH Oxidase Activity in a Murine Model of Sleep Apnea
por: Nair, Deepti, et al.
Publicado: (2011)

Diaphragm Abnormalities in Patients with End-Stage Heart Failure: NADPH Oxidase Upregulation and Protein Oxidation
por: Ahn, Bumsoo, et al.
Publicado: (2017)

NADPH Oxidase-Derived ROS Induced by Chronic Intermittent Hypoxia Mediates Hypersensitivity of Lung Vagal C Fibers in Rats
por: Yang, Chang-Huan, et al.
Publicado: (2016)

Is Aberrant Reno-Renal Reflex Control of Blood Pressure a Contributor to Chronic Intermittent Hypoxia-Induced Hypertension?
por: AlMarabeh, Sara, et al.
Publicado: (2019)

Effects of aerobic exercise on cardiac function and gene expression of NADPH oxidases in diaphragm muscle of rats with aortic stenosis-induced heart failure
por: Janini Gomes, Mariana, et al.
Publicado: (2023)

HIF-1α-Mediated, NADPH Oxidase-Derived ROS Contributes to Laryngeal Airway Hyperreactivity Induced by Intermittent Hypoxia in Rats
por: Lin, You Shuei, et al.
Publicado: (2020)

Revealing the roles of GORK channels and NADPH oxidase in acclimation to hypoxia in Arabidopsis
por: Wang, Feifei, et al.
Publicado: (2017)

NADPH Oxidase and Neurodegeneration
por: Hernandes, Marina S, et al.
Publicado: (2012)

A Role for NADPH Oxidase in Antigen Presentation
por: Gardiner, Gail J., et al.
Publicado: (2013)

NADPH Oxidases and Their Role in Atherosclerosis
por: Poznyak, Anastasia V., et al.
Publicado: (2020)

NADPH Oxidases in Pain Processing
por: Kallenborn-Gerhardt, Wiebke, et al.
Publicado: (2022)

NADPH Oxidases in Aortic Aneurysms
por: Salmon, Morgan
Publicado: (2022)

Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs
por: Lucking, Eric F., et al.
Publicado: (2018)

Diaphragm Muscle Weakness in an Experimental Porcine Intensive Care Unit Model
por: Ochala, Julien, et al.
Publicado: (2011)

Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity
por: Deep, Gagan, et al.
Publicado: (2016)

Decreased NADPH oxidase expression and antioxidant activity in cachectic skeletal muscle
por: Sullivan-Gunn, Melanie J., et al.
Publicado: (2011)

Regulation of Smooth Muscle Cell Proliferation by NADPH Oxidases in Pulmonary Hypertension
por: Huetsch, John C., et al.
Publicado: (2019)

NADPH Oxidase 4 Contributes to Myoblast Fusion and Skeletal Muscle Regeneration
por: Youm, Tae Hyun, et al.
Publicado: (2019)

Xanthine Oxidase Mediates Hypoxia-Inducible Factor-2α Degradation by Intermittent Hypoxia
por: Nanduri, Jayasri, et al.
Publicado: (2013)

Autophagy-Associated Atrophy and Metabolic Remodeling of the Mouse Diaphragm after Short-Term Intermittent Hypoxia
por: Giordano, Christian, et al.
Publicado: (2015)

Chronic sustained hypoxia-induced redox remodeling causes contractile dysfunction in mouse sternohyoid muscle
por: Lewis, Philip, et al.
Publicado: (2015)

Natural Compounds as Modulators of NADPH Oxidases
por: Maraldi, Tullia
Publicado: (2013)

NADPH Oxidases and Mitochondria in Vascular Senescence
por: Salazar, Gloria
Publicado: (2018)

NADPH oxidases: Current aspects and tools
por: Schröder, Katrin
Publicado: (2020)

Architecture of the NADPH oxidase family of enzymes
por: Ogboo, Blessing C., et al.
Publicado: (2022)

(Poly)phenols and the regulation of NADPH oxidases
por: Fraga, Cesar G., et al.
Publicado: (2023)

Differential Expression of NADPH Oxidases Depends on Skeletal Muscle Fiber Type in Rats
por: Loureiro, Adriano César Carneiro, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jrrmplhif2fgvmgrjrcdnv9aee