Cell Transitions Contribute to Glucocorticoid-Induced Bone Loss

Glucocorticoid-induced bone loss is a toxic effect of long-term therapy with glucocorticoids resulting in a significant increase in the risk of fracture. Here, we find that glucocorticoids reciprocally convert osteoblast-lineage cells into endothelial-like cells. This is confirmed by lineage tracing...

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Detalles Bibliográficos
Autores principales: Qiao, Xiaojing, Wu, Xiuju, Zhao, Yan, Yang, Yang, Zhang, Li, Cai, Xinjiang, Ma, Jocelyn A., Ji, Jaden, Lyons, Karen, Boström, Kristina I., Yao, Yucheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377921/
https://www.ncbi.nlm.nih.gov/pubmed/37508475
http://dx.doi.org/10.3390/cells12141810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377921/
https://www.ncbi.nlm.nih.gov/pubmed/37508475
http://dx.doi.org/10.3390/cells12141810

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