Escin Activates Canonical Wnt/β-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3β in Cultured Human Dermal Papilla Cells

Abnormal inactivation of the Wnt/β-catenin signaling pathway is involved in skin diseases like androgenetic alopecia, vitiligo and canities, but small-molecule activators are rarely described. In this study, we investigated the stimulatory effects of escin on the canonical Wnt/β-catenin signaling pa...

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Detalles Bibliográficos
Autores principales: Shin, Jae Young, Kim, Jaeyoon, Choi, Yun-Ho, Lee, Sanghwa, Kang, Nae-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377929/
https://www.ncbi.nlm.nih.gov/pubmed/37504289
http://dx.doi.org/10.3390/cimb45070373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377929/
https://www.ncbi.nlm.nih.gov/pubmed/37504289
http://dx.doi.org/10.3390/cimb45070373

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