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Escin Activates Canonical Wnt/β-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3β in Cultured Human Dermal Papilla Cells
Abnormal inactivation of the Wnt/β-catenin signaling pathway is involved in skin diseases like androgenetic alopecia, vitiligo and canities, but small-molecule activators are rarely described. In this study, we investigated the stimulatory effects of escin on the canonical Wnt/β-catenin signaling pa...
Autores principales: | Shin, Jae Young, Kim, Jaeyoon, Choi, Yun-Ho, Lee, Sanghwa, Kang, Nae-Gyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377929/ https://www.ncbi.nlm.nih.gov/pubmed/37504289 http://dx.doi.org/10.3390/cimb45070373 |
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