Cargando…

Chemokine/ITGA4 Interaction Directs iPSC-Derived Myogenic Progenitor Migration to Injury Sites in Aging Muscle for Regeneration

The failure of muscle to repair after injury during aging may be a major contributor to muscle mass loss. We recently generated muscle progenitor cells (MPCs) from human-induced pluripotent stem-cell (iPSC) cell lines using small molecules, CHIR99021 and Givinostat (Givi-MPCs) sequentially. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Ashraf, Muhammad, Tipparaju, Srinivas M., Kim, Joung Woul, Xuan, Wanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378040/
https://www.ncbi.nlm.nih.gov/pubmed/37508502
http://dx.doi.org/10.3390/cells12141837