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Ca(2+)-Driven Selectivity of the Effect of the Cardiotonic Steroid Marinobufagenin on Rabbit Sinoatrial Node Function
The synergy between Na(+)-K(+) pumps, Na(+)-Ca(2+) exchangers, membrane currents and the sarcoplasmic reticulum (SR) generates the coupled-clock system, which governs the spontaneous electrical activity of heart sinoatrial node cells (SANCs). Ca(2+) mediates the degree of clock coupling via local Ca...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378090/ https://www.ncbi.nlm.nih.gov/pubmed/37508546 http://dx.doi.org/10.3390/cells12141881 |