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Amyloid β(1–42) Oligomers Induce Galectin–1(S8) O–GlcNAcylation Leading to Microglia Migration

Protein O–GlcNAcylation has been associated with neurodegenerative diseases such as Alzheimer’s disease (AD). The O–GlcNAcylation of the Amyloid Precursor Protein (APP) regulates both the trafficking and the processing of the APP through the amyloidogenic pathway, resulting in the release and aggreg...

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Detalles Bibliográficos
Autores principales: Arrazola Sastre, Alazne, Luque Montoro, Miriam, Llavero, Francisco, Zugaza, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378097/
https://www.ncbi.nlm.nih.gov/pubmed/37508540
http://dx.doi.org/10.3390/cells12141876