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Metformin Treatment Reduces CRC Aggressiveness in a Glucose-Independent Manner: An In Vitro and Ex Vivo Study

SIMPLE SUMMARY: In 2020, colorectal cancer (CRC) was ranked third among the most common cancers in the world, and second in terms of cancer-related mortality. Epithelial–mesenchymal transition (EMT) is mainly recognized by the loss of epithelial markers (such as E-cadherin) and cell movement activat...

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Detalles Bibliográficos
Autores principales: Boutaud, Marie, Auger, Clément, Verdier, Mireille, Christou, Niki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378121/
https://www.ncbi.nlm.nih.gov/pubmed/37509386
http://dx.doi.org/10.3390/cancers15143724