ROP16 of Toxoplasma gondii Inhibits Innate Immunity by Triggering cGAS-STING Pathway Inactivity through the Polyubiquitination of STING

cGAS-STING signaling is a major pathway in inducing type Ⅰ IFN, which plays a crucial role in the defense against T. gondii infection. In contrast, T. gondii develops multiple strategies to counteract the host defense, causing serious diseases in a wide range of hosts. Here, we demonstrate that T. g...

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Detalles Bibliográficos
Autores principales: Jin, Qi-Wang, Yu, Ting, Pan, Ming, Fan, Yi-Min, Huang, Si-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378213/
https://www.ncbi.nlm.nih.gov/pubmed/37508526
http://dx.doi.org/10.3390/cells12141862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378213/
https://www.ncbi.nlm.nih.gov/pubmed/37508526
http://dx.doi.org/10.3390/cells12141862

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