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N-Acetylaspartate Drives Oligodendroglial Differentiation via Histone Deacetylase Activation
An unmet clinical goal in demyelinating pathologies is to restore the myelin sheath prior to neural degeneration. N-acetylaspartate (NAA) is an acetylated derivative form of aspartate, abundant in the healthy brain but severely reduced during traumatic brain injury and in patients with neurodegenera...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378218/ https://www.ncbi.nlm.nih.gov/pubmed/37508525 http://dx.doi.org/10.3390/cells12141861 |