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Optimization of a Luteolin-Loaded TPGS/Poloxamer 407 Nanomicelle: The Effects of Copolymers, Hydration Temperature and Duration, and Freezing Temperature on Encapsulation Efficiency, Particle Size, and Solubility

SIMPLE SUMMARY: Luteolin is a natural compound from plants with various medicinal benefits, including anti-cancer activities. However, luteolin has limited use clinically due to its low solubility and absorption into the body. Hence, the objective of this research work was to formulate and optimize...

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Detalles Bibliográficos
Autores principales: Mod Razif, Muhammad Redza Fahmi, Chan, Siok Yee, Widodo, Riyanto Teguh, Chew, Yik-Ling, Hassan, Masriana, Hisham, Shairyzah Ahmad, Rahman, Shamima Abdul, Ming, Long Chiau, Tan, Ching Siang, Lee, Siew-Keah, Liew, Kai Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378229/
https://www.ncbi.nlm.nih.gov/pubmed/37509402
http://dx.doi.org/10.3390/cancers15143741