The Molecular Pathogenesis of Tumor-Suppressive miR-486-5p and miR-486-3p Target Genes: GINS4 Facilitates Aggressiveness in Lung Adenocarcinoma

SIMPLE SUMMARY: Two microRNAs (miRNAs) (miR-486-5p and miR-486-3p) derived from pre-miR-486 acted as tumor-suppressive miRNAs in lung adenocarcinoma (LUAD). We identified seven genes (MKI67, GINS4, RRM2, HELLS, MELK, TIMELESS, and SAPCD2) involved in the malignant phenotype of LUAD cells coordinatel...

Descripción completa

Detalles Bibliográficos
Autores principales: Tomioka, Yuya, Suetsugu, Takayuki, Seki, Naohiko, Tanigawa, Kengo, Hagihara, Yoko, Shinmura, Masahiro, Asai, Shunichi, Kikkawa, Naoko, Inoue, Hiromasa, Mizuno, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378275/
https://www.ncbi.nlm.nih.gov/pubmed/37508549
http://dx.doi.org/10.3390/cells12141885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378275/
https://www.ncbi.nlm.nih.gov/pubmed/37508549
http://dx.doi.org/10.3390/cells12141885

Ejemplares similares