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The Molecular Pathogenesis of Tumor-Suppressive miR-486-5p and miR-486-3p Target Genes: GINS4 Facilitates Aggressiveness in Lung Adenocarcinoma

SIMPLE SUMMARY: Two microRNAs (miRNAs) (miR-486-5p and miR-486-3p) derived from pre-miR-486 acted as tumor-suppressive miRNAs in lung adenocarcinoma (LUAD). We identified seven genes (MKI67, GINS4, RRM2, HELLS, MELK, TIMELESS, and SAPCD2) involved in the malignant phenotype of LUAD cells coordinatel...

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Detalles Bibliográficos
Autores principales:	Tomioka, Yuya, Suetsugu, Takayuki, Seki, Naohiko, Tanigawa, Kengo, Hagihara, Yoko, Shinmura, Masahiro, Asai, Shunichi, Kikkawa, Naoko, Inoue, Hiromasa, Mizuno, Keiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378275/ https://www.ncbi.nlm.nih.gov/pubmed/37508549 http://dx.doi.org/10.3390/cells12141885

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