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Reduced Tie2 in Microvascular Endothelial Cells Is Associated with Organ-Specific Adhesion Molecule Expression in Murine Health and Endotoxemia

Endothelial cells (ECs) in the microvasculature in organs are active participants in the pathophysiology of sepsis. Tyrosine protein kinase receptor Tie2 (Tek; Tunica interna Endothelial cell Kinase) is thought to play a role in their inflammatory response, yet data are inconclusive. We investigated...

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Detalles Bibliográficos
Autores principales: Zwiers, Peter J., Lucas, Jacqueline P. F. E., Jongman, Rianne M., van Meurs, Matijs, Popa, Eliane R., Molema, Grietje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378325/
https://www.ncbi.nlm.nih.gov/pubmed/37508516
http://dx.doi.org/10.3390/cells12141850