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Intratumoural Delivery of mRNA Loaded on a Cationic Hyper-Branched Cyclodextrin-Based Polymer Induced an Anti-Tumour Immunological Response in Melanoma

SIMPLE SUMMARY: The frequency of metastatic melanoma, an extremely deadly malignancy, is rapidly increasing worldwide. Recently, messenger RNA (mRNA) injections have emerged as a promising treatment option. While mRNA therapies have demonstrated significant promise, the stability of the naked form r...

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Detalles Bibliográficos
Autores principales: Khazaei Monfared, Yousef, Mahmoudian, Mohammad, Zakeri-Milani, Parvin, Cecone, Claudio, Hayashi, Tomoya, Ishii, Ken J., Conde, João, Matencio, Adrián, Trotta, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378402/
https://www.ncbi.nlm.nih.gov/pubmed/37509409
http://dx.doi.org/10.3390/cancers15143748