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Intratumoural Delivery of mRNA Loaded on a Cationic Hyper-Branched Cyclodextrin-Based Polymer Induced an Anti-Tumour Immunological Response in Melanoma
SIMPLE SUMMARY: The frequency of metastatic melanoma, an extremely deadly malignancy, is rapidly increasing worldwide. Recently, messenger RNA (mRNA) injections have emerged as a promising treatment option. While mRNA therapies have demonstrated significant promise, the stability of the naked form r...
Autores principales: | Khazaei Monfared, Yousef, Mahmoudian, Mohammad, Zakeri-Milani, Parvin, Cecone, Claudio, Hayashi, Tomoya, Ishii, Ken J., Conde, João, Matencio, Adrián, Trotta, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378402/ https://www.ncbi.nlm.nih.gov/pubmed/37509409 http://dx.doi.org/10.3390/cancers15143748 |
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