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Grade Progression and Intrapatient Tumor Heterogeneity as Potential Contributors to Resistance in Gastroenteropancreatic Neuroendocrine Tumors

SIMPLE SUMMARY: Neuroendocrine neoplasms (NENs) have a varied biology. While well-differentiated neuroendocrine tumors (NETs) typically demonstrate indolent behavior, a subset of these tumors exhibits rapid growth, and eventual resistance to various treatments over time is the rule. We discuss intra...

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Detalles Bibliográficos
Autores principales: Varghese, Diana Grace, Del Rivero, Jaydira, Bergsland, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378410/
https://www.ncbi.nlm.nih.gov/pubmed/37509373
http://dx.doi.org/10.3390/cancers15143712