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A Shiga Toxin B-Subunit-Based Lectibody Boosts T Cell Cytotoxicity towards Gb3-Positive Cancer Cells

Aberrant glycosylation plays a crucial role in tumour progression and invasiveness. Tumour-associated carbohydrate antigens (TACAs) represent a valuable set of targets for immunotherapeutic approaches. The poor immunogenicity of glycan structures, however, requires a more effective and well-directed...

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Detalles Bibliográficos
Autores principales: Tomisch, Jana, Busse, Vincent, Rosato, Francesca, Makshakova, Olga N., Salavei, Pavel, Kittel, Anna-Sophia, Gillon, Emilie, Lataster, Levin, Imberty, Anne, Meléndez, Ana Valeria, Römer, Winfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378424/
https://www.ncbi.nlm.nih.gov/pubmed/37508560
http://dx.doi.org/10.3390/cells12141896