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A Shiga Toxin B-Subunit-Based Lectibody Boosts T Cell Cytotoxicity towards Gb3-Positive Cancer Cells
Aberrant glycosylation plays a crucial role in tumour progression and invasiveness. Tumour-associated carbohydrate antigens (TACAs) represent a valuable set of targets for immunotherapeutic approaches. The poor immunogenicity of glycan structures, however, requires a more effective and well-directed...
Autores principales: | Tomisch, Jana, Busse, Vincent, Rosato, Francesca, Makshakova, Olga N., Salavei, Pavel, Kittel, Anna-Sophia, Gillon, Emilie, Lataster, Levin, Imberty, Anne, Meléndez, Ana Valeria, Römer, Winfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378424/ https://www.ncbi.nlm.nih.gov/pubmed/37508560 http://dx.doi.org/10.3390/cells12141896 |
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