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Oral Delivery of mRNA Vaccine by Plant-Derived Extracellular Vesicle Carriers

mRNA-based vaccines were effective in contrasting SARS-CoV-2 infection. However, they presented several limitations of storage and supply chain, and their parenteral administration elicited a limited mucosal IgA immune response. Extracellular vesicles (EVs) have been recognized as a mechanism of cel...

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Detalles Bibliográficos
Autores principales: Pomatto, Margherita A. C., Gai, Chiara, Negro, Federica, Massari, Lucia, Deregibus, Maria Chiara, De Rosa, Francesco Giuseppe, Camussi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378442/
https://www.ncbi.nlm.nih.gov/pubmed/37508491
http://dx.doi.org/10.3390/cells12141826