Role of a Novel Heparanase Inhibitor on the Balance between Apoptosis and Autophagy in U87 Human Glioblastoma Cells

Background: Heparanase (HPSE) is an endo-β-glucuronidase that cleaves heparan sulfate side chains, leading to the disassembly of the extracellular matrix, facilitating cell invasion and metastasis dissemination. In this research, we investigated the role of a new HPSE inhibitor, RDS 3337, in the reg...

Descripción completa

Detalles Bibliográficos
Autores principales: Manganelli, Valeria, Misasi, Roberta, Riitano, Gloria, Capozzi, Antonella, Mattei, Vincenzo, Caglar, Tuba Rana, Ialongo, Davide, Madia, Valentina Noemi, Messore, Antonella, Costi, Roberta, Di Santo, Roberto, Sorice, Maurizio, Garofalo, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378526/
https://www.ncbi.nlm.nih.gov/pubmed/37508554
http://dx.doi.org/10.3390/cells12141891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378526/
https://www.ncbi.nlm.nih.gov/pubmed/37508554
http://dx.doi.org/10.3390/cells12141891

Ejemplares similares