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Disruption of the Mammalian Ccr4–Not Complex Contributes to Transcription-Mediated Genome Instability

The mammalian Ccr4–Not complex, carbon catabolite repression 4 (Ccr4)-negative on TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts at different cellular levels to regulate gene expression. It is involved in the control of the cell cycle, chromatin modific...

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Detalles Bibliográficos
Autores principales: Hagkarim, Nafiseh Chalabi, Hajkarim, Morteza Chalabi, Suzuki, Toru, Fujiwara, Toshinobu, Winkler, G. Sebastiaan, Stewart, Grant S., Grand, Roger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378556/
https://www.ncbi.nlm.nih.gov/pubmed/37508532
http://dx.doi.org/10.3390/cells12141868