Targeted Protein Degradation: Principles and Applications of the Proteasome

The proteasome is a multi-catalytic protease complex that is involved in protein quality control via three proteolytic activities (i.e., caspase-, trypsin-, and chymotrypsin-like activities). Most cellular proteins are selectively degraded by the proteasome via ubiquitination. Moreover, the ubiquiti...

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Detalles Bibliográficos
Autores principales: Kim, Yosup, Kim, Eun-Kyung, Chey, Yoona, Song, Min-Jeong, Jang, Ho Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378610/
https://www.ncbi.nlm.nih.gov/pubmed/37508510
http://dx.doi.org/10.3390/cells12141846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378610/
https://www.ncbi.nlm.nih.gov/pubmed/37508510
http://dx.doi.org/10.3390/cells12141846

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