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Therapeutic Targeting of DNA Replication Stress in Cancer

This article reviews the currently used therapeutic strategies to target DNA replication stress for cancer treatment in the clinic, highlighting their effectiveness and limitations due to toxicity and drug resistance. Cancer cells experience enhanced spontaneous DNA damage due to compromised DNA rep...

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Detalles Bibliográficos
Autores principales: Gu, Long, Hickey, Robert J., Malkas, Linda H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378776/
https://www.ncbi.nlm.nih.gov/pubmed/37510250
http://dx.doi.org/10.3390/genes14071346